Pem, and

Anabolic A. Strategies. Even

in the recovery phase, endogenous anabolic activity remains depressed

. This is the case in elderly patients, those

chronic diseases or in patients with unintentional weight loss. Adequacy of the substrate (1. 5 g / kg / day protein) can not be

quickly begin restoring muscle mass. However, the machine is capable of very rapid rate of protein synthesis

, regardless of the age, if stimulated

anabolic agents. Body

research during correction of protein energy malnutrition

(PEM), have shown that much of >> << weight gain after unintentional weight loss of

catabolic disease represents the addition of fat and

extracellular fluid, not added protein mass. Not

anabolic stimulation is the cause. currently in clinical practice has dual character. First, amino

drove in channel protein synthesis in the cell through

of cell surface receptors in muscle. Metabolic pathways, >> << use of anabolic agents to achieve protein synthesis

may be different, but the result is increased

muscle. The second anti-catabolic effect. All anabolic >> << agents appear to decrease protein degradation, possibly

blocking cellular receptors cortisol. In >> << lack of sufficient anabolic activity >> << energy to the way protein synthesis is not sufficient and

excess energy stored as fat. Anabolic hormones >> << are used more often in

people with thin or mass loss of the existing PEM, and

optimal nutrition and supplementary anabolic stimulus of resistance exercise <<. Growth Hormone >>

usually done in the pituitary (0. 8 mg / day) and

is a potent endogenous anabolic hormone. It is in the

high concentrations in childhood when the growth spurt >> << and gradually decreases with age or chronic disease. Growth Hormone

binds to specific receptors cell leading to a number

metabolic effects, some due to the direct activity of hormones on tissue

, especially in the liver. Other effects caused by

release of insulin growth factor-1, which is

ranozazhyvlyayuschym powerful effects .. Agents such as glutamine and arginine in

reported increase growth hormone release. Plasma HGH

level decreases after severe trauma or sepsis, thereby lowering

normal anabolic activity. Numerous studies

use of exogenous growth hormone in patients with injuries and burns and other injuries

demonstrated their effectiveness

better anabolic and speed healing. An

to support muscle mass. Average

dose growth hormone used 0. 1 to 0. 2 mg / kg body weight in

weight, or about 10 times the normal endogenous production of

. The number of complications were recorded;

The most common is hyperglycemia, due to anti-insulin activity >>. << Increase insulin is often required. Also >> <<, growth hormone is very expensive, and it can increase >> << morbidity and mortality. It parenterally in

certain groups of people in intensive care. Exogenous

growth hormone, is now obtained genetic processes are

only approved U.S. Food lasix generic no prescription and Drug (FDA)

for use in children with low growth or dwarfism. However, as an orphan drug, it was used for

anabolic activity, especially in burn patients and patients

violation of healing. .